Gate Bioscience is creating a new category of medicines called Molecular Gates. Our therapeutics are small molecules that selectively eliminate harmful extracellular proteins at their origin, inside the cell. We are working to develop a small molecule therapeutic to selectively eliminate prion protein (PrP) in the brain. If successful, this work could lead to an orally available PrP-lowering medicine: in effect, a pill to treat or prevent prion disease. Gate Bioscience’s Prion therapeutic is in preclinical development and is not yet ready for clinical trials.
– Science article – Foiling Deadly Prions
– Our website – https://www.gatebio.com/
Below is a link to Erik Minikel’s blog sharing his perspective on the Ionis Community Statement regarding the recruiting pause of the Prion Disease clinical trial.
Link – Why the ION717 trial is paused
from: CureFFI.org
So nice to see a member of our prion research community acknowledged. Many of you, who have donated funds in memory of your loved ones to the CJDSGN to support our prion researchers in Australia, would have helped provide funds for some of Andy’s work.
From Cosmos Studio
